Gene

plekhf2

ID

ZDB-GENE-040426-884

Name

pleckstrin homology domain containing, family F (with FYVE domain) member 2

Symbol

plekhf2 Nomenclature History

Previous Names

zgc:56073 (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have phosphatidylinositol binding activity. Predicted to be involved in protein transport. Predicted to localize to early endosome membrane and endoplasmic reticulum. Orthologous to human PLEKHF2 (pleckstrin homology and FYVE domain containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56073 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With plekhf2 Human Ortholog

No data available

Associated With plekhf2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000306	FYVE zinc finger
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR017455	Zinc finger, FYVE-related
Domain	IPR037871	Phafin, PH domain
Domain	IPR047966	Pleckstrin homology domain-containing family F member 2, FYVE domain
Family	IPR051765	Pleckstrin homology domain-containing family F
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type